The Moors Murderer Ian Brady has died at a high-security psychiatric hospital in Merseyside.
Brady, 79, who tortured and murdered five children along with his partner Myra Hindley, was confirmed to have died by Mersey Care NHS Foundation Trust.
Hindley died in prison in 2002 at the age of 60.
It was not clear what the cause of Brady’s death was but he was reported to be receiving palliative care from nurses around the clock in recent days.
Two private ambulances were seen leaving the grounds of the hospital on Monday night.
Brady and Hindley together sexually tortured and murdered five children and teenagers, aged between ten and 17, in the 1960s.
Four of their victims were buried on Saddleworth Moor near Manchester.
The remains of one victim, 12-year-old Keith Bennett, have never been found despite extensive searches as recently as 2014.
Brady’s death means that his family will probably never find out his final resting place.
The killer was sentenced to life in 1966 after being convicted of the murders of John Kilbride, aged 12, Lesley Ann Downey, 10, and Edward Evans, 17.
He later confessed to the murders of Keith Bennett, 12, and Pauline Reade, 16, together with Hindley.
He has been held at the Ashworth secure psychiatric hospital for 32 years after being transferred there in 1985 to be treated for psychopathy.
Brady had been force-fed for many years after going in hunger strike from 1999 – though a court hearing in 2013 heard that he regularly ate toast and soup.
The killer had launched a legal bid in 2013 to be transferred out of the prison to a hospital so that he could stop being fed through a tube and be allowed to die if he wishes.
He was turned down at the mental health tribunal on the grounds that he was insane.
Brady, who had continued his legal challenges into his final months, was reportedly being given constant care from nurses specialising in terminal cancer, according to The Sun newspaper.